Associate Scientist II, Downstream Process Development New Haven, Connecticut

Location New Haven, Connecticut, United States

Job ID R-232084

Date posted 21/07/2025

This is what you will do:

The Associate Scientist II is responsible for performing assigned experimental tasks to support the development and optimization of manufacturing processes for Alexion’s biotherapeutic candidates. The Associate Scientist II will work routinely in collaboration with other members of Biologics Drug Substance Process Development, Technology Transfer and Analytical Sciences, including all other groups in Product Development and Clinical Supply.

You will be responsible for:

• Conducts experimental studies to develop, optimize, and characterize manufacturing purification processes for biotherapeutic candidates

• Performs experimental studies to support scale up of manufacturing processes or troubleshooting of issues at manufacturing scale as required for therapeutic proteins

• Documents study results in notebooks, forms, and technical reports

• Assists in laboratory management including ordering and maintenance

You will need to have:

• BS (with 2+ years of experience) or MS degree in Biochemistry, Chemistry, Chemical Engineering, or related field from an accredited university

• Problem solving skills: Works cross-functionally to solve routine technical problems

• Scientific Inquisitiveness: Understands background of assigned technical tasks to be a resource for others, demonstrates ability to delve deeper into technical topics, seeks to incorporate ideas from conferences or literature into work processes

• Communication skills: Routinely delivers effective technical presentations within functional group, Drafts, edits and finalizes technical documents without templates and with minimal supervision, Works collaboratively with own group to achieve shared objectives

• Technical expertise: Conducts assigned routine tasks in the laboratory with limited supervision, conducts training in certain technical areas, Implements complicated study plans with supervision

• Decision Quality: Regularly interacts with peers across functions, Understands priority of assigned tasks with limited supervision

• Proficiency with various MS Office programs, including Word, Excel, Outlook, and PowerPoint

• Accountability: Works with supervisor and co-workers to ensure assigned tasks are completed, demonstrates ability to manage aspects of a technical project

• The duties of this role are generally conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

• Experience in any area of biologics process development (cell culture and/or purification)

• Experience performing chromatographic protein purification

• Experience with Unicorn programming and operation of AKTA and other chromatography skids

• Experience in nano filtration and ultrafiltration/diafiltration

• Experience with Statistical Design of Experiments Software (e.g., JMP)

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.