SCIENTIST II, BIOMOLECULAR INTERACTIONS

Job ID: R00130598

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.

Job Description

AbbVie's Biotherapeutics and Genetic Medicine, Protein Science Group, is seeking a highly skilled and self-motivated scientist to join our Biomolecular Interaction Team. This role offers the opportunity to make significant contributions to all Discovery Research Therapeutic Areas and Projects by providing analytical and functional characterization of our biopharmaceutical products, including monoclonal antibodies, multi-specifics and antibody-like biologics. The ideal candidate will have a strong understanding of high-throughput biologics screening and characterization methods (e.g., SPR, BLI, ELISA, FACS, etc.) and possess a solid foundation in protein sciences and antibody discovery with a proven ability to work effectively on cross-functional teams. This is an excellent opportunity for a highly motivated scientist to make a meaningful impact in a collaborative and innovative setting. Join us in bringing innovative medicines to patients!

Key Responsibilities

• Independently develop and execute SPR (Biacore and Carterra platforms) assays to generate objective selection criteria for panels of antibodies, multispecifics, and antibody-like biologics.
• Evaluate and integrate protein-protein interaction technologies (e.g., SPR, BLI, ELISA, etc.) to support therapeutic candidate selection, demonstrating strong problem-solving skills.
• Implement high-throughput epitope binning for large panels of monoclonal antibodies and develop deep knowledge of antibody sequence/function relationships.
• Perform antibody Fc characterization studies to support regulatory submissions.
• Understand relevant scientific literature and apply the theoretical framework to solve problems within the scientific discipline in a timely manner.
• Continuously seek to improve existing laboratory methods and processes.
• Analyze, document, and report data concisely and rigorously.
• Provide project updates, analyses, and advice to cross-functional teams and senior management.
• Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents.

Qualifications

• BS or MS in biology, chemistry, biochemistry or related field with typically 7+ (BS) or 5+ (MS) years of experience.
• Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.
• Strong knowledge and hands-on experience with analytical/functional characterization of biologics using Surface Plasmon Resonance (SPR) platforms (e.g., Biacore T200 and 8K, Carterra LSA).
• Broad technical knowledge of various analytical, biophysical, and structural methods, such as SEC, MS, HDX-MS, X-ray crystallography, DSF, DLS, etc.
• Experience with biologics, monoclonal antibodies and/or protein therapeutics.
• Excellent organizational skills with the capacity to manage multiple projects and tasks simultaneously within timelines.
• Goal-oriented team player with excellent verbal and written communication skills and a strong can-do attitude and can operate effectively in a fast-paced, multi-disciplinary environment.
• Ability to adapt to rapid changes in project priorities and timelines.

Key AbbVie Competencies

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance.
• Learns fast, grasps the “essence” and can change course quickly when indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. Salary: $73,000 - $138,500

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.
  

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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https://www.abbvie.com/join-us/reasonable-accommodations.html