Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Key Accountabilities/Core Job Responsibilities:
- Provide clinical, scientific, and strategic leadership for translational and early clinical projects, including leading early clinical-stage project teams
- Responsible for the design, execution, analysis, interpretation, and presentation of clinical and translational studies
- Plan, organize, and direct the activities of clinical trials, including development of clinical protocols and amendments, investigator brochures, and clinical study reports
- Provide medical monitoring support, including evaluation of safety, pharmacology, and efficacy of ongoing and completed studies
- Establish and implement exploratory pharmacodynamic, diagnostic, and biomarker plans in conjunction with partners in Clinical Pharmacology and Translational Sciences
- Interact with external thought leaders, including advisory boards, to support clinical and translational development
- Participate in the development and execution of strategies for new product development and lifecycle growth, including regulatory and investigator interactions
- Prepare literature reviews, external presentations, and publications as appropriate
Qualifications/Skills:
- MD or MD/PhD physician-scientist with strong understanding of translational disease biology and a track record of designing and executing innovative early-stage trials
- 2+ years (Medical Director) or 5+ years (Senior Medical Director) clinical development experience in industry
- A strong track record in team leadership, development of clinical-regulatory strategies, and/or industry-academic collaborations
- Training in adult or pediatric neurology or research experience in neuroscience preferred but not required
- Interest and flexibility to work across multiple indications with high unmet need and ability to develop expertise in new disease areas quickly
- Excellent presentation skills and ability to communicate effectively with external partners and with preclinical, biomarker, biostatistical and computational scientists
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.