Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

We are seeking an experienced Vice President of Oncology Sales to lead, scale and develop our sales team for our ultra-sensitive liquid biopsy & precise monitoring oncology test, Northstar®. This position will have significant responsibility and impact within the organization and will be considered part of the ELT. The VP of Oncology Sales will have full P&L/budget responsibility and will oversee a team of 30+ reps, managers, and area directors. This is an opportunity to build a world class sales team with the gold standard of Oncology Diagnostic testing, in a market that is expected to reach approximately $25-35 billion globally by 2030.

Responsibilities:

• Develop and execute comprehensive sales strategies to drive adoption of Northstar® and related oncology testing solutions
• Responsible for building and scaling the sales team structure, including; hiring and developing sales representatives, managers, and directors. 
• Lead, mentor, and support Sales Directors and their regional teams to drive performance and growth.
• Drive revenue growth and consistently meet or exceed quarterly and annual sales targets
• Design and implement territory expansion plans to maximize market coverage and sales efficiency
• Collaborate cross-functionally with Marketing, Product, Operations, and other departments to ensure alignment and seamless execution of go-to-market strategies
• Build and maintain relationships with key opinion leaders, major cancer centers, healthcare systems, and strategic accounts
• Provide regular reporting and insights to Executive Leadership Team on market trends, competitive landscape, and sales performance
• Continuously refine sales processes, tools, and methodologies to increase effectiveness and scalability
• Foster a culture of excellence, accountability, and continuous improvement within the sales organization
• Represent BillionToOne at oncology conferences, trade shows, and other external events

Qualifications:

• 15+ years of progressive sales leadership experience in the laboratory/diagnostics industry
• Experience building and managing a team of 100 or more sales representatives through a multi-layer team structure
• Proven track record of consistently exceeding sales targets and building high-performing teams
• Experience scaling sales organizations in high-growth environments
• Deep understanding of healthcare provider sales cycles and decision-making processes
• Experience in oncology diagnostics and/or precision medicine market preferred
• Knowledge of liquid biopsy landscape and competing technologies
• Strong relationships with oncology key opinion leaders and cancer centers
• Demonstrated success in territory expansion and sales infrastructure development
• Strong analytical skills with the ability to translate data into actionable insights
• Experience presenting to executive leadership teams and boards
• Bachelor's degree required; MBA or advanced degree preferred

Key Attributes:

• Ambitious mentality with a strong sense of urgency and bias toward action
• Quick learner with appetite to master the business and product inside out
• Hands-on leader who embodies a "no job too big or too small" mentality
• Ability to build authentic trust at all levels within the organization
• Deep passion for Northstar® testing and BillionToOne's mission to transform cancer care
• Genuine commitment to team development and people-first leadership
• Exceptional relationship builder with high emotional intelligence
• Creative problem solver with a solutions first mindset
• Effective communicator who can deliver difficult messages while maintaining team morale
• Humble approach, free from ego and not seeking personal spotlight

Additional Details:

• Location: Flexible, with preference for Central or Western US
• Travel Requirements: Extensive (approximately 50%) including field work, cancer center visits, executive leadership meetings, headquarters visits, and quarterly manager meetings

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Free UNITY Complete NIPT tests for employees & spouses
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)

At BillionToOne, we are proud to offer a combination of a (1) base pay + uncapped commissions  (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, the base salary is $260,100 per year with $125,000 of commissions at plan and stock options valued at $187,500 per year ($750,000 over 4 years), for a total compensation of $572,600 per year. Commissions are uncapped and can be significant.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

About BillionToOne

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA—a breakthrough that's already transformed the lives of over 500,000 patients worldwide.

Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024—with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated—one that remains authentically collaborative and transparent even as we've scaled.

Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started.

At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work.

Ready to help us change the world, one diagnosis at a time?

Learn more at www.billiontoone.com